Can they trigger inflammatory responses?

The short answer is YES.

Some probiotics may actually possess inflammatory properties, as they may prompt immune activation and subsequent cytokine release. Cytokines can either promote inflammatory responses or control them.

The body's immune function identifies and responds to a foreign bacterium, whether friendly or potentially harmful. Whether or not immune activation and an inflammatory response follow depends on the bacterium.

What are SILENT Probiotics?

A silent probiotic provides beneficial support that helps avoid immune activation and the subsequent release of potentially harmful cytokines. Silent probiotics improve the landscape of the gut microbiome without inflaming the gut and peripheral tissues.

NEW Zenbiome™ DUAL contains probiotic bacterium Bifidobacterium longum 35624™ and psychobiotic bacterium Bifidobacterium longum 1714™. BOTH are SILENT probiotic species.

Both Bifidobacterium longum 35624™ and Bifidobacterium longum 1714™ have a special exopolysaccharide coating called the EPS (extracellular polymeric substance or exopolysaccharide) layer, a supportive “invisibility cloak” that may prevent an overreactive hyperimmune response. Support from this fancy sugar coat helps 35624™ and 1714™ go incognito, avoiding immune activation. Thus, the EPS layer assists 1714™ and 35624™ in traversing the gastric mucosa in a state of neutrality.1

Mechanism of Action:

Within four hours of consumption, bacteria-sampling dendritic cells begin engulfing the 1714™ and 35624™ strains. Once dendritic cells fully engulf the probiotics, they support IL10 production and immune function tolerance via T cell polarization. IL-10 is a cytokine that provides support to dampen inflaming responses. Support from both 1714™ and 35624™ helps block Th1, Th2, and Th17 cell production and promotes regulatory T cell production. When colonic visceral hypersensitivity is a concern, these are critical functions. 2-4

One of the most powerful aspects of the Bifidobacterium species is their unique ability to support a reduction in inflammatory responses by upregulating cytokines that dampen inflaming responses and inhibiting the release of cytokines that promote them.3

The Advantages of Research-Backed Microbiome Support

Many nutraceutical companies have yet to investigate or even consider how their probiotics could ignite inflammatory responses. This lack of research could lead to potentially harmful outcomes for clients. Companies must do their due diligence and thoroughly research their products' safety and efficacy. Microbiome Labs' formulas are supported by scientific evidence and clinical research. We take costly and time-consuming extra steps to clinically validate to the highest scientific standards, confirming through research that our final formulations work within the body as promoted and expected.

Our Mission is connecting the dots of the human microbiome with Science You Can Trust.

Try NEW Zenbiome™ DUAL, the psychobiotic/probiotic combo supplement that pioneers a new path to supporting optimal digestive comfort and mood self-regulation via numerous innovative, science-based actions.